Li-Fraumeni Syndrome (LFS) is linked to a mutation in the TP53 tumor suppressor gene.

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Many with TP53 mutations affectionately refer to themselves as mutants- think finding power in something that is out of your control. Andi Last found a powerful way to express how "With my breast cancer battle finished, I can shine a spotlight on my war: Mutant Vs Monster. I am a Mutant. I have a genetic mutation that gives me a Monster of a rare disorder called Li-Fraumeni Syndrome (LFS), which makes me prone to getting all sorts of different cancers." Thank You Andi Last for supporting living LFS and raising awareness in such a powerful way.

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We hear this a lot in our support groups. LFS is hard enough, be gentle with yourself. ... See MoreSee Less

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My name is Andi Last. That’s my husband Jay Last in the video with me. I’m the mutant, and he’s my warrior. In March 2015, at the age of 41, I was diagnosed with breast cancer. Not long after, I learned that I have a very rare inherited disorder called Li Fraumeni Syndrome, or LFS, which makes me prone to getting all kinds of different cancers. In simple terms, we’re all born with two copies of a cancer suppressing gene … read more

The 2016 Summer Olympics are underway in Brazil. We watch as the world comes together in Rio to celebrate and honor feats of strength, endurance and quite a bit of luck. Some athletes do their best to make their own luck, while others acknowledge the hereditary gifts that enable them to compete athletically at such a spectacular level. There was talk of the city of Rio’s struggles to get everything in order to host the games. Yet the Brazilians are … read more