Li-Fraumeni Syndrome (LFS) is linked to a mutation in the TP53 tumor suppressor gene.

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If someone has multiple cancers, or certain cancers that are associated with LFS, physicians begin to wonder if a genetic mutation such as in TP53 could be why. Here’s Nicole’s story. ... See MoreSee Less

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There are many hereditary cancer syndromes, Li Fraumeni Syndrome is one. There are multiple sets of criteria that medical professionals use to determine if someone should be tested for LFS. These are a few. If you think you might be at risk for LFS, medical professionals such as genetic counselors can help assess your risk and if genetic testing is a good option. ... See MoreSee Less

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By Andi Last I took this photo and wrote the following in May of 2019, on my 10 year anniversary of moving home to San Diego from Australia. As I wrote it, I was awaiting the results of yet another mammogram. I find that gathering feelings of hope and gratitude helps me manage scanxiety – and every day of living with LFS. The results of the mammogram were benign. _____ In the past ten years, I’ve developed countless lines around my eyes and grey in my … read more

What is Metformin? Metformin is an oral medication that decreases the amount of sugar made in the liver, helps the body use sugar and recognize the insulin receptors again. First created from French Lilac in the 1920’s to help manage diabetes, Metformin was put aside when insulin was developed. Decades later, in the 50’s the French began clinical trials and Metformin eventually became widely used in Canada, the UK and in the US during the mid 90’s to treat type … read more